Abstract
Five children in one family living in London developed diphtheria due to Corynebacterium diphtheriae var. gravis between 12 and 19 September 1975. Five days before the onset of symptoms in the first case the family had moved from Birmingham where subsequent investigation led to the detection of two pharyngeal diphtheria carriers aged 10 and 4 years who were next-door neighbours of the affected family and who had arrived from Bangladesh six weeks previously, on 28 July 1975. They were considered to be the source of infection. Two secondary sub-clinical cases occurred in London but there was no other spread of infection.
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