Abstract
A theoretical model for the diffusion study of a molecule in suspension in a continuous medium is presented. This model provides a realistic representation of the release by diffusion of a drug in a polymeric matrix at a concentration C 0 above its solubility C s in the medium, in the case where the molecule diffuses into the receptor, similar to what occurs with the donor. The release kinetics is a function of t 1 2 . It contains a numerical parameter β which is a function of the ratio C 0/C s. The table of values of β is g variant of the method of analysis is also presented which has the advantage of not requiring knowledge of the solubility of the molecule in the system, which is often hard to measure in practice. In the experimental section, the theoretical models are validated using the diffusion of testosterone in suspension in a silicic acid gel.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
