Abstract
Objective To investigate the effects of different insulin application methods in the treatment of coma caused by diabetic ketoacidosis. Methods A total of 100 patients with coma caused by diabetic ketoacidosis treated at our hopsital from January to December, 2017 were enrolled in the study. They were randomly divided into a study group and a control group. The control group was treated with insulin intravenous injection, while the study group with continuous infusion of insulin pump. Results Before the treatment, the levels of fasting blood glucose and postprandial blood glucose in the study group were (17.45±2.68) mmol/L and (23.78±3.40) mmol/L, with no statistical differences from those in the control group (both P>0.05). After the Treatment, the levels of fasting blood glucose and postprandial blood glucose in the study group were (9.01±2.02) mmol/L and (10.12±2.50) mmol/L, which were lower than those in the control group (P 0.05). Conclusion The effect of continuous insulin pump infusion in the treatment of coma caused by diabetic ketoacidosis is statistically different from that of intravenous insulin injection, but it can control blood sugar indicators more effectively, shorten the times to turn urine and blood ketone negative and the time for blood glucose reaching the standard. Key words: Insulin; Application mode; Diabetic ketoacidosis; Coma; Application effect
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