Abstract

Summary LDH isoenzyme patterns in fundic and pyloric mucosa and in corresponding muscular layers of the rat stomach were examined (six pooled samples from 12 rats). The LDH isoenzyme pattern and the were used as indicators for the prevalence calculated ratio of monomer H:M synthesis of either an aerobic or an anaerobic type of metabolism. The most striking and most constant feature was the relative prevalence of LDH 1 in the mucosa of the fundic gland area, and vice versa—the prevalence of LDH 5 in the mucosa of the pyloric gland area. From the LDH isoenzyme patterns it is concluded that an aerobic type of metabolism is relatively prevalent in the mucosa of the fundic gland area, and an anaerobic type in the mucosa of the pyloric gland area. The difference between the LDH isoenzyme patterns in the fundic area muscular layer and in the pyloric muscular layer was smaller than that between the mucosae of the corresponding parts. A possible explanation of the observed facts is given.

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