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Abstract
Differential inductive capacities among liver tissues of several animals were examined by anticipating the correlation between the capacity and the completness of perisinusoidal basement membrane. The reacting tissue was competent ectoderm of gastrula of Triturus pyrrhogaster, and the inductive effects of livers on the ectoderm were tested by explantation method. The inductive effect of livers being devoid of the membrane (chick and guinea pig) was neural and the tissues having the dense well-developed membrane (reptiles) produced an assembly of neural and meso-dermal tissues, such as notochord and somite or muscle. The livers with the membrane being of intermediate grade of development (calf, Triturus and mouse) induce mesodermal tissues, but not frequently, together with neural tissue or alone. The liver tissue was more active in mesodermal induction in proportion to the completeness of the perisinusoidal basement membrane. On the basis of these data the difference in inductive capacity among liver tissues from different kinds of animals were discussed.
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