Abstract
The aim of present study was to evaluate the diagnostic value of multislice computed tomography coronary angiography in patients with left bundle branch block. Twenty-four patients who underwent both multislice computed tomography coronary angiography and invasive coronary angiography were enrolled in the study. Findings of these imaging modalities were compared in order to determine the sensitivity, specificity, positive predictive value, and negative predictive value of multislice computed tomography angiography in identifying hemodynamically significant stenoses (> or =50%). All segments > or =2 mm in diameter were visually assessed independently from their degree of calcification and image quality. In total, 328 segments were analyzed. The Spearman correlation coefficient between multislice computed tomography and invasive coronary angiography was 0.76 (P<0.0001). On a per-segment basis, sensitivity, specificity, positive predictive value, and negative predictive value of multislice computed tomography angiography were 75%, 97.7%, 72%, and 98%, respectively; on a per-vessel basis, these values were 77.8%, 92.3%, 70%, and 94.7%, respectively; on a per-patient basis - 81.8%, 84.6%, 81.8%, and 84.6%, respectively. Multislice computed tomography coronary angiography provides a high diagnostic accuracy in detecting significant coronary artery stenoses in patients with left bundle branch block.
Highlights
Twenty-four patients who underwent both multislice computed tomography coronary angiography and invasive coronary angiography were enrolled in the study
Findings of these imaging modalities were compared in order to determine the sensitivity, specificity, positive predictive value, and negative predictive value of multislice computed tomography angiography in identifying hemodinamically significant stenoses (350%)
Multislice computed tomography coronary angiography provides a high diagnostic accuracy in detecting significant coronary artery stenoses in patients with left bundle branch block
Summary
Remiantis intervencinės vainikinių arterijų angiografijos rodmenimis, nustatyta daugiapjūvės kompiuterinės tomografijos diagnostinė vertė (jautrumas, specifiškumas, teigiama ir neigiama prognostinės vertės), identifikuojant hemodinamiškai reikšmingas (350 proc.) spindžio stenozes. Atliktų su 64 pjūvių DKT aparatu, įvertinti 31,5 mm skersmens segmentai, nepriklausomai nuo jų kokybės, jautrumas buvo 94 proc., specifiškumas – 97 proc., teigiama prognostinė vertė – 87 proc., neigiama prognostinė vertė – 99 proc. S. Ghostine ir kolegų tyrimo duomenimis, pacientams, kuriems diagnozuota KHPKB, 64 pjūvių DKT angiografijos jautrumas buvo 72 proc., specifiškumas – 99 proc., teigiama prognostinė vertė – 91 proc., neigiama prognostinė vertė – 97 proc. Šešiems iš 30 pacientų intervencinė vainikinių arterijų angiografija neatlikta, tačiau tik du iš jų šios procedūros atsisakė, nes DKT tyrimo metu stenozės vainikinėse arterijose nenustatyta, todėl įtaka tyrimo duomenims neturėtų būti reikšminga. The aim of present study was to evaluate the diagnostic value of multislice computed tomography coronary angiography in patients with left bundle branch block
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