Abstract
Aim: Diagnostic efficiency of liquid based cytology compared with conventional pap
 Methods: The present analytical study entitled was conducted in the Department of Obstetrics and Gynecology, Nalanda Medical College and Hospital, Patna, Bihar, India over the period of 1 year. The study includes total 100 subjects.
 Results: Mean age of the study population was 39.12 years. Majority belongs to 30-40 years of age group. Vaginal discharge was the major problem reported by the study subjects. There were statistically significant differences of satisfactory/unsatisfactory rate and Diagnostic efficacy i.e. sensitivity and specificity of LBC is greater than CPS for evaluation of cervical cytology.
 Conclusions: the present study concluded that LBC may improve the sample's quality, reduce the number of unsatisfactory smear and increases the diagnostic efficacy in comparison to CPS.
 Keywords: Cervical cancer, Conventional pap smear, Liquid-based cytology, Sensitivity, Specificity.
Highlights
Cervical cancer ranks second in incidence and mortality behind breast cancer in lower HDI settings
Aim: Diagnostic efficiency of liquid based cytology compared with conventional pap Methods: The present analytical study entitled was conducted in the Department of Obstetrics and Gynecology, Nalanda Medical College and Hospital, Patna, Bihar, India over the period of 1 year
There were statistically significant differences of satisfactory/unsatisfactory rate and Diagnostic efficacy i.e. sensitivity and specificity of Liquid based cytology (LBC) is greater than CPS for evaluation of cervical cytology
Summary
Cervical cancer ranks second in incidence and mortality behind breast cancer in lower HDI settings. Cervical cancer is the second most common female cancer in women aged 15 to 44 years in India. I. Persistent infection of the cervix with high-risk types of human papillomavirus (HPV) has been established as a necessary (but not sufficient) cause for the development of cervical cancer.ii HPV is a very common sexually transmitted infection that is usually acquired soon after the initiation of sexual activity. A small portion of the sample taken from the patient is transferred to the conventional Pap slide; most of it is discarded along with the sampling device. These limitations may lead to inaccuracies and equivocal diagnoses when using this methodology
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