Abstract
Various causes are attributed to postoperative thrombocytopenia in a patient who has undergone cardiac bypass. The incidence of heparin-induced thrombocytopenia (HIT) in Indians is 5.6%. We present here 2 cases of postcoronary artery bypass graft surgery; both were presenting with >50% drop in platelets on day 5 of heparin injection, both had acute kidney injury, and one also had transaminitis. The detection of anti-heparin PF4 antibodies was performed by rapid ID Micro-gel typing system in both the cases and one was confirmed as HIT.Heparin/PF4 Antibody card test and heparin-induced platelet aggregation test (PAT) other was negative and was finally diagnosed as disseminated intravascular coagulation. Thus rapid diagnosis was reached and patients were managed accordingly, which is different in both conditions.
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