Abstract
Glandular abnormalities comprise less than one-quarter of the diseases affecting the uterine cervix. The acquisition of knowledge on the epidemiological and biological features of glandular lesions of the cervix has occurred more slowly compared with the progress associated with squamous cell lesions. This difference is principally due to the greater prevalence of squamous cells lesions compared with that of glandular lesions. Evidence-based management guidelines are lacking for the most severe forms of glandular abnormalities of the cervix, in particular for invasive adenocarcinomas. This review summarizes the epidemiology, natural history and diagnosis of glandular abnormalities of the cervix and the current debate on the management of cervical in situ and invasive adenocarcinomas.
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