Abstract
We describe a patient with an acute and persistent pulmonary embolus, identified after five weeks of heparin therapy (25,000 IU per day, administered intravenously) by indium-111 platelet scintigraphy. The diagnosis was confirmed by pulmonary angiography and later at surgery. Platelet scintigraphy convincingly demonstrated the continual uptake of platelets onto the surface of the thrombus despite anticoagulant therapy. It might provide a noninvasive means of identifying nonresolving pulmonary emboli.
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