Abstract

Diabetic nephropathy (DN) is a clinical syndrome characterized by kidney lesions and formation narrow or diffusion glomerulosclerosis, which later becomes kidney failure. It is manifested by persistent albuminuria (>300 mg/day or >200 μg/min), that is confirmed on at least 2 occasions 3–6 months apart, with a progressive decrease in glomerular filtration rate (GFR) and elevated arterial blood pressure (BP).

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