Dexmedetomidine attenuates perioperative anxiety and dragging pain for concomitant strabismus surgery

Abstract

Objective To evaluate the effects of Dexmedetomidine on perioperative anxiety and dragging pain for concomitant strabismus surgery administrated before Lidocaine local anesthesia.Methods 30 elective concomitant strabismus patients with American Association of Anesthesia (ASA)score of Ⅰ ～Ⅱwere quasi-randomly divided into 2 equal-sized groups:the control group (Lidocaine subconjunctival infiltration anesthesia) and Dexmedetomidine group (intravenous injection of 1.0 μg/kg Dexmedetomidine before local anesthesia).Patients were visited one day before and after operation,and self-rating anxiety scale (SAS) were recorded.Ramsay score was evaluated for both groups to determine the degree of sedation.Narcotrend monitoring was also performed for Dexmedetomidine group to assess the depth of anesthesia.The operation duration and the perioperative dragging pain were recorded for both groups.Results SAS scores showed significant difference between pre-operative and post-operative periods in Dexmedetomidine group (P＜ 0.05).The Dexmedetomidine group has shorter surgery duration with only one case experienced dragging pain in contrast with 10 cases in the control group (P ＜ 0.05).Dexmedetomidine treatment maintained a Ramsay score of Ⅱ with stable vital signs and well cooperation with ophthalmologist during the operation.Conclusion Dexmedetomidine assisted with Lidocaine local anesthesia provides evident benefits for patients undergoing concomitant strabismus surgery.Compared with simple Lidocaine local anesthesia,dexmedetomidine effectively attenuates perioperative anxiety and provides better cooperation with the ophthalmologists. Key words: Dexmedetomidine; Surgery, strabismus ; Anxiety