Abstract
BackgroundContinuous progression of lesions despite an adequate treatment has been described in tubercular multifocal serpiginoid choroiditis. Reported treatments for this paradoxical response include systemic steroids, immunosuppressive drugs, and intravitreal methotrexate. We describe the use of dexamethasone intravitreal implants in a patient presenting with this condition.FindingsA 46-year-old woman sought medical attention for scotomas in her left eye. Tests suggested multifocal serpiginoid choroiditis associated with latent tuberculosis infection, and hence, she was started on anti-tuberculosis drugs in combination with corticosteroids. Given that lesions progressed despite this treatment, we began treatment with dexamethasone intravitreal implants. After injection of the second implant, we succeeded in inactivating the inflammatory process.ConclusionsDexamethasone intravitreal implants may be a suitable alternative to systemic steroids or immunosuppressive therapy in the management of continuous progression of lesions in tubercular multifocal serpiginoid choroiditis.
Highlights
Continuous progression of lesions despite an adequate treatment has been described in tubercular multifocal serpiginoid choroiditis
Dexamethasone intravitreal implants may be a suitable alternative to systemic steroids or immunosuppressive therapy in the management of continuous progression of lesions in tubercular multifocal serpiginoid choroiditis
Multifocal serpiginoid choroiditis (MSC) is a rare entity producing chronic recurrent progressive inflammation of the retinal pigment epithelium and choriocapillaris that is associated with latent tuberculosis infection [1]
Summary
Continuous progression of lesions despite an adequate treatment has been described in tubercular multifocal serpiginoid choroiditis. Conclusions: Dexamethasone intravitreal implants may be a suitable alternative to systemic steroids or immunosuppressive therapy in the management of continuous progression of lesions in tubercular multifocal serpiginoid choroiditis. Introduction Multifocal serpiginoid choroiditis (MSC) is a rare entity producing chronic recurrent progressive inflammation of the retinal pigment epithelium and choriocapillaris that is associated with latent tuberculosis infection [1].
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