Development of the second “add-on PET” prototype: A head coil with DOI-PET detectors for MRI

Abstract

We are developing a PET/MRI system based on 4-layered depth-of-interaction (DOI) detectors integrated with a birdcage RF-coil. The PET detectors are placed close to the objective to achieve both high sensitivity and high spatial resolution even at the edge of the field of view (FOV). In a previous study, we reported the first prototype which had a single detector ring to show a proof-of-concept and lower than 1.6 mm spatial resolution was achieved. However, the axial FOV of the prototype was only 1 cm, which could not be extended due to the size of the readout circuit boards. In this paper, we finally constructed a new RF-coil for the second prototype, which is combined with 24 DOI-PET detectors. We evaluated performance in simultaneous measurements. The second prototype consisted of an RF-coil and 24 PET detector units with two PET detectors each. The detector units were shielded with carbon fiber shielding boxes. Each PET detector consisted of a 14 × 14 × 4-layer array of lutetium fine silicate (LFS) crystals (1.9 mm × 1.9 mm × 4.0 mm), an 8 × 8 multi-pixel photon counter module (MPPC, S11206-0808FC(X)) and a readout circuit board with an ASIC. The RF coil was dedicated to a 3T MRI (MAGNETOM Verio, Siemens). We conducted performance tests of the second prototype in simultaneous measurements. As a result, the influence of the MRI measurements on the PET performance was found to be negligible. In addition, secondary magnetic field due to the eddy current effect can be reduced, compared with the previous prototype system.