Abstract
One of the major benefits of biomedicine is the use of biocomposites as wound dressings to help improve the treatment of injuries. Therefore, the main objective of this study was to develop and characterize biocomposites based on bacterial cellulose (BC) with different concentrations of collagen and starch and characterize their thermal, morphological, mechanical, physical, and barrier properties. In total, nine samples were produced with fixed amounts of glycerol and BC and variations in the amount of collagen and starch. The water activity (0.400–0.480), water solubility (12.94–69.7%), moisture (10.75–20.60%), thickness (0.04–0.11 mm), water vapor permeability (5.59–14.06 × 10−8 g·mm/m2·h·Pa), grammage (8.91–39.58 g·cm−2), opacity (8.37–36.67 Abs 600 nm·mm−1), elongation (4.81–169.54%), and tensile strength (0.99–16.32 MPa) were evaluated and defined. In addition, scanning electron microscopy showed that adding biopolymers in the cellulose matrix made the surface compact, which also influenced the visual appearance. Thus, the performance of the biocomposites was directly influenced by their composition. The performance of the different samples obtained resulted in them having different potentials for application considering the injury type. This provides a solution for the ineffectiveness of traditional dressings, which is one of the great problems of the biomedical sector.
Highlights
The last five decades have witnessed tremendous growth in the field of biomaterial science and engineering because of vast investments in the development of new products, including wound dressings [1]
Based on the intrinsic properties of bacterial cellulose (BC), collagen, and starch as well as the potential for application of biocomposites resulting from the combination of these biomaterials, this study aimed to develop and characterize biocomposites based on BC with different concentrations of collagen and starch and characterize them with respect to their thermal, mechanical, morphological, and physical and barrier properties, with the aim of their potential application as wound dressings
Eight different biocomposites based on BC, collagen, and starch and the control were produced according to Table 1
Summary
The last five decades have witnessed tremendous growth in the field of biomaterial science and engineering because of vast investments in the development of new products, including wound dressings [1]. It is known that a satisfactory material that covers the wound to prevent microbiological contamination and promotes a suitable environment for tissue regeneration is required for effective wound healing [10]. Biomaterials such as polysaccharides (glycans) [11,12,13,14] and proteins [15,16] present an interesting alternative for this application due to their intrinsic properties that are considered essential for a dressing such as biocompatibility, non-toxicity, ability to adsorb bioactive molecules, and biodegradability [17]
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