Abstract

Mammary gland is altered gland present in skin whose main function in females is that it acts as a lactating gland while in males it is non-functional. When the sample of tissue of mammary gland is observed under microscope it was found that there are 2 major types of tissues which are present. These tissues are epithelial and stromal tissues. The epithelial component of the breast consists of 2 major parts: terminal duct-lobular unit (TDLU) which performs the main secretory function during lactation, and large duct system which performs the function of collection and drainage of secretions; both are interconnected to each other. During the menstrual age of a female patient there are different number of tissues (connective and adipose) is present in the mammary gland these tissues mainly perform as the support system for the mammary gland. Acini, ducts, and lobule are enclosed in intralobular stroma and is mainly formed of connective tissue(loose) myxomatous stroma and some dispersed lymphocyte. The ductal carcinoma is very serious Pathology of breast which is now a major concern in developed country and to a certain extent in developing countries also. There are many major risk factors which are responsible for the same. Some may be of lifestyle based or of genetic based. The treatment for the disease is now possible with advancement in the medical science.
 Purpose for this review article is: Determine the cause affecting factors influencing factors and pathos physiological background of development of DCIS also to describe the gene involved in alteration of cell to enhance tumorous growth and the treatment therapy involved alongside the disease.

Highlights

  • The mammary gland, or breast, is the most important component in the pectoral area

  • The subareolar plexus drains into the anterior or pectoral group of lymph nodes, as does the majority of lymph from the breast [2]. These lymphatic fluid at the end drain into the lymph nodes which are present around the mammary gland namely as apical and anternal mammary, they flow from the profound surface of the mammary gland by crossing the muscle of chest the pectoralis major and a fascia that is clavipectoral fascia [4]

  • Increased lean mass after menopause is linked to greater levels of inflammatory markers, which are thought to have a role in the development of DUCTAL CARCINOMA IN SITU of mammary glands in females [8]

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Summary

INTRODUCTION

The mammary gland, or breast, is the most important component in the pectoral area. The breast is located in the pectoral region's superficial fascia. The axillary nodes are where the majority of the lymphatic fluid is drained from the mammary gland [2,3]. The subareolar plexus drains into the anterior or pectoral group of lymph nodes, as does the majority of lymph from the breast [2]. These lymphatic fluid at the end drain into the lymph nodes which are present around the mammary gland namely as apical and anternal mammary, they flow from the profound surface of the mammary gland by crossing the muscle of chest the pectoralis major and a fascia that is clavipectoral fascia [4]. Tumors that infiltrate thin-walled vessels are more common [5]

DCIS CAN BE DIAGNOSED BY VARIOUS WAYS
DEFINITION AND HISTOPATHOLOGICAL FEATURES
RISK FACTORS FOR DCIS
RADIOLOGY DESCRIPTION
TREATING OF DCIS
HER2 VACCINES
Findings
CONCLUSION

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