Determination of Bioactive and Pharmaceutical Components of Croton bonplandianus by GC-MS Analysis

Abstract

The present study sought to analyze the chloroformic extract of aerial parts of the Indian medicinal plant Croton bonplandianus by GC-MS analysis and to explore the presence of major phytoconstituents. Gas chromato-graphy–mass spectrometric (GC–MS) analysis was carried out on the chloroformic extract of aerial parts of Croton bonplandianus for identification of phytocomponents in the plant while the mass spectra of the components found in the extract was matched with the National Institute of Standards and Technology (NIST) library. There are 59 bioactive components were identified from chloroformic extract of Croton bonplandianus. Hence, it is of interest to investigate the presence of phytoconstituents from the chloroformic extract of Croton bonplandianus by using GC-MS method. The highest peak area (%) of 21.710 was obtained by Phenol,2-methyl1-5-(1,2,2-trimethyl cyclo pentyl)-(s) (Retention time 28.236) and the lowest peak area (%) of 0.76 was obtained by Bicyclo [7,2,0] undecane,10,10-dimethyl1-2,6-bis (methylene)-[1S-1R*,9S*)] (Retention time 29.396). Results confirmed the presence of therapeutically potent compounds in the plant extract. This study is helpful to predict the formula and structure of biomolecules which can be used as drugs and further investigation may lead to the development of drug formulation.