Abstract
The relationship between serum α-tocopherol level and many of its possible determinants was available in 1,373 cancer-free Finnish men and women age 40–79 years. Dietary data were available from a subsample of 301 persons. The mean α-tocopherol level in the serum samples stored at −20°C was 8.6 mg/liter among men and 10.5 mg/liter among women. Intake of margarine, vegetable oils, and green vegetables predicted the serum level of α-tocopherol. Altogether six food groups accounted for about 10% of the variation. The levels also varied with age, geographical area, type of population, occupation, socioeconomic status, and marital status. They were positively correlated with serum cholesterol and serum vitamin A in both sexes, and with body mass index and serum selenium in men. Altogether these variables accounted for over 40% of the variation in α-tocopherol levels. The level of serum α-tocopherol, which is associated with the dietary intake of vitamin E, is dependent upon living conditions.
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