Abstract
Objective The objective of this study was to examine the predictors of fatigue 6 and 12 months after surgical treatment in women with early-stage breast cancer (BC group) and in women with benign breast problems (BBP group) in a prospective follow-up study. Methods Women entered the study prior to diagnosis and completed questionnaires on personality factors, psychological factors, and social support. Fatigue was assessed 6 and 12 months after diagnosis (BBP group) or surgical treatment (BC group). Clinical data were taken from medical records. Results In the BC group ( n=117), fatigue at 6 months was predicted by trait anxiety ( P<.001) and extraversion ( P<.05). Trait anxiety ( P<.05), extraversion ( P<.05), and depressive symptoms ( P<.05) predicted fatigue at 12 months. In the BBP group ( n=190), the predictors were trait anxiety ( P<.001) for fatigue at 6 months, and trait anxiety ( P<.001) and neuroticism ( P<.01) for fatigue at 12 months. Conclusion Many patients who are already fatigued before diagnosis remain tired regardless of diagnosis. Trait anxiety is strongly related to fatigue in both groups.
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