Abstract

Abstract A total method verification program is presented, composed of the initial developing laboratory’s method validation process and the end user’s method evaluation studies. Both processes escalate in a cyclic fashion and the communicative pathway is the method transfer process. The participating laboratories acquire data by the intralaboratory procedures described and the cross-over studies entail the interlaboratory (collaborative) procedures described. During the entire process, the diagnostic techniques described result in the detection and determination of error in the methodology.

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