Abstract

Microneedles have been recently given much attention as a novel way for transdermal drug delivery. In this paper, the mechanics of microneedle insertion into soft tissue during drug delivery and also the changes in the forces and moments of the microneedle is to be presented. A non-linear displacement of the microneedle insertion into the soft tissue is expressed as a quadratic polynomial function and solved using Galerkin technique. The geometrical behavior of the microneedle tip is to be considered in the analytical model. The graphical analysis of the analytical model are presented using MATLAB. The analytical model helps to improve the microneedle design by minimizing the pain of insertion and increasing the mechanical strength.

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