Abstract

Results Out of total of 134 HIV-positive patients, 41 patients had cutaneous manifestations, 28 were male (68.29%) and 13 female (31.70%). Most patients were in the age group 16-30 years (58.53%). The majority of patients belonged to the urban area (65.85%) and had a low educational and socioeconomic status (only 56.09% patients graduated secondary school; 82.92% of the patients were unemployed). The prevailing route of transmission was parenteral (41.46%), most patients had stage C3 HIV disease (56.09%), and only 24.39% of patients had undetectable viral load. Most patients were undergoing ARV regimen (80.48%), 12.19% were naive and 7.31% had ceased therapy. 17 patients had 2 concomitant dermatological manifestations (41.46%), while 13 were treated for only one skin disease (31.70%); 19.51% patients were diagnosed with 3 concurrent dermatological diseases and 7.31% with 4 simultaneous skin disorders. The most common HIV-related dermatological manifestations were oral candidiasis (78.04%), seborrheic dermatitis (14.63%), lipodystrophy (12.19%), tinea corporis (7.31%), herpes zoster (4.87%), syphilis (4.87%) and cellulitis (4.87%). CD4 counts ranged between 2-1551 cells/μL, with a mean CD4 of 139 cells/μL. Oral candidiasis was correlated with a mean CD4 count of 305 cells/μL, seborrheic dermatitis was related to a mean CD4 of 233 cells/μL, while lipodystrophy was associated with a mean CD4 of 202 cells/μL.

Highlights

  • The aim of the study was to establish the most common dermatological manifestations in HIV hospitalized patients and to correlate the status of cutaneous diseases in relation with the CD4 cell count

  • Most patients were undergoing ARV regimen (80.48%), 12.19% were naive and 7.31% had ceased therapy. 17 patients had 2 concomitant dermatological manifestations (41.46%), while 13 were treated for only one skin disease (31.70%); 19.51% patients were diagnosed with 3 concurrent dermatological diseases and 7.31%

  • Oral candidiasis was correlated with a mean CD4 count of 305 cells/μL, seborrheic dermatitis was related to a mean CD4 of 233 cells/μL, while lipodystrophy was associated with a mean CD4 of 202 cells/μL

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Summary

Introduction

The aim of the study was to establish the most common dermatological manifestations in HIV hospitalized patients and to correlate the status of cutaneous diseases in relation with the CD4 cell count. Dermatological manifestations common in hospitalized HIV patients From The 10th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof Dr Matei Bals” Bucharest, Romania. Background The aim of the study was to establish the most common dermatological manifestations in HIV hospitalized patients and to correlate the status of cutaneous diseases in relation with the CD4 cell count.

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