Abstract

Inhalation is the main route for aerosol entering the human body. Many occupational lung diseases are associated with exposure to fiber aerosol in the workplace. However, very few studies to date have been conducted for investigating fiber deposition in the human airway. As a result, there is a notable lack of information on the nature of the fiber deposition pattern in the human respiratory tract. With this in mind, this research consisted of a large number of experimental works to investigate the effects of fiber dimension on the deposition pattern for a human nasal airway. Carbon fibers with uniform diameter (3.66 μm) and polydispersed length were adopted as the test material. Deposition studies were conducted by delivering aerosolized carbon fibers into a nasal airway replica (encompassing the nasal airway regions from vestibule to nasopharynx) at constant inspiratory flow rates of 7.5, 15, 30, and 43.5 l/min. Fibers deposited in each nasal airway region were washed out and the length distribution was...

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