Abstract
In 1987, collection of efficacy and safety information of children on Growth Hormone (GH) treatment started within KIGS. Today, 8887 patients are enrolled from 28 countries. Parental, perinatal and pretreatment information are given for the major groups in the Table. During this 5 year period, the age at start of treatment has been maintained except for the reduction from 9.7 to 5.0 years in the congenital GHD children. The height at start of treatment has increased for all groups with an average of 0.4 SDS. The male dominance has been kept and the parental height has been below average for all patients but those with malignancies. This KIGS database will continue to provide us with important information about children on GH treatment in order to achieve earlier diagnoses, more optimal treatment for different etiology groups as well as collecting safety information.
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