Abstract

Probabilistic maps of white matter pathways related to motor, somatosensory, auditory, visual, and limbic functions, and major white matter tracts (the corpus callosum, the inferior fronto-occipital fasciculus, and the middle cerebellar peduncle) were applied to evaluate the developmental trajectories of these tracts, using longitudinal diffusion tensor imaging (DTI) obtained in term-born and preterm-born healthy infants. Nineteen term-born and 30 preterm-born infants completed MR scans at three time points: Time-point 1, 41.6±2.7 postmenstrual weeks; Time-point 2, 46.0±2.9 postmenstrual weeks; and Time-point 3, 50.8±3.7 postmenstrual weeks. The DTI-derived scalar values (fractional anisotropy, eigenvalues, and radial diffusivity) of the three time points are available in this Data article.

Highlights

  • Probabilistic maps of white matter pathways related to motor, somatosensory, auditory, visual, and limbic functions, and major white matter tracts were applied to evaluate the developmental trajectories of these tracts, using longitudinal diffusion tensor imaging (DTI) obtained in term-born and preterm-born healthy infants

  • Each image was transfactors formed to the JHU-neonate atlas using dual-channel large deformation diffeomorphic metric mapping

  • The probabilistic maps of pathways related to motor, somatosensory, auditory, visual, and limbic functions, and major white matter tracts [1] (freely downloadable from) were applied to evaluate the developmental trajectories of these tracts, using longitudinal diffusion tensor imaging obtained in term-born and preterm-born infants

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Summary

Experimental design

The probabilistic maps of pathways related to motor, somatosensory, auditory, visual, and limbic functions, and major white matter tracts (the corpus callosum, the inferior fronto-occipital fasciculus, and the middle cerebellar peduncle) [1] (freely downloadable from (http://cmrm.med.jhmi.edu/)) were applied to evaluate the developmental trajectories of these tracts, using longitudinal diffusion tensor imaging obtained in term-born and preterm-born infants. The FA, e0, e1, e2, and radial diffusivity were measured at each time point. GCC Rt.Thal-PSC Lt.V1-V4 Rt.ILF Rt.AR Rt.UNC Rt.IFO Lt.UNC BCC Lt.Thal-PSC Lt.ILF Rt.CST MCP Rt.Premotor-PMC Rt.V1-V4 Lt.OR Lt.IFO Rt.CG Rt.V1 -MT Rt.OR Lt.CG Lt.Premotor-PMC Lt.V1-MT Lt.AR SCC Lt.CST term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm term preterm. PSC Lt.V1-MT Lt.ILF Lt.Premotor -PMC Rt.Premotor -PMC SCC Lt.ThalPSC GCC Lt.OR Rt.ILF Rt.CST Lt.CG Rt.V1-V4 Rt.IFO MCP Lt.AR Rt.UNC Rt.CG Lt.UNC Rt.V1-MT Lt.IFO Rt.OR Lt.CST Rt.AR.

Participants
MRI scans
Findings
Image processing
Full Text
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