Abstract
Letters, Comments, and Corrections1 August 1972Defibrination or Primary Fibrinolysis?RICHARD B. SOLOMON, M.D.RICHARD B. SOLOMON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-77-2-328_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The paper entitled "Defibrination in Acute Pancreatitis" (Ann Intern Med76:73-76, 1972) requires some comment. Although the data support the presence of a fibrinolytic state (proteolysis of casein, fibrinogen degradation products, diminished plasminogen level, shortened euglobulin lysis time, prolonged thrombin time), there is no definite evidence favoring associated defibrination. Normal levels of factors V and VIII, moderate depression of factors VII and IX, and the absence of schistocytes are not characteristic of defibrination. The reduced platelet count could be explained by the precedingL-asparaginase therapy. Tests for the presence of fibrin monomer (for example, protamine sulfate), thought... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Division of Hematology Queens Hospital Center affiliated with the Long Island Jewish-Hillside Medical Center Jamaica, N.Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1972Volume 77, Issue 2Page: 328-328KeywordsAcute pancreatitisFibrinFibrinogenFibrinolysisPlateletsProtaminesProteolysisThrombin Issue Published: 1 August 1972 PDF downloadLoading ...
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