Abstract
A 19-year old student with temporal lobe epilepsy since the age of 15 presented with a first multifocal demyelinating clinical event (right optic neuritis, right hypaesthesia). Three years later a second relapse led to the diagnosis of relapsing-remitting multiple sclerosis (MS). Another 3 years later 6 relapses with increasing severity within 15 months signalized highly active MS. Disease activity was paused by steroids, plasma exchange and induction treatment with cyclophosphamide. A 7-year clinical steadiness was achieved by a 2 year maintenance treatment with mitoxantrone and deescalation, subsequently. After 2 more relapses, natalizumab treatment was initiated. After 16 months the patient was again deescalated to interferon β-1b. Since then, the patient developed no more relapses.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
