Decoding the chemical clues: The role of advancements in forensic toxicology

Abstract

Forensic toxicology, a crucial discipline in criminal investigations, has undergone significant advancements in recent years. This article delves into the realm of emerging techniques, analytical methods, and innovative applications that are revolutionizing the field. Advanced analytical techniques, such as high-resolution mass spectrometry, have enhanced the sensitivity and specificity of drug detection, enabling the identification of trace-level substances, including novel psychoactive substances (NPS). Emerging analytical methods, such as non-targeted screening approaches and biosensors, offer rapid and portable solutions for on-site drug detection. The article highlights the innovative applications of forensic toxicology, extending beyond traditional analyses. In postmortem toxicology, improved techniques aid in determining cause of death and assessing time of drug administration. In driving under the influence evaluation, roadside screening devices and pharmacodynamic models provide valuable insights into drug impairment. And in drug abuse monitoring and treatment, toxicological data informs public health interventions and treatment strategies. The article concludes by emphasizing the importance of continuous advancements in forensic toxicology to stay ahead of the growing complexity of toxicological challenges and address the ethical considerations surrounding advanced techniques. It underscores the significance of collaboration between forensic toxicologists, analytical chemists, pharmacologists, and clinicians to foster knowledge sharing and accelerate progress in this vital field.