Abstract
Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra etal. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein.
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