Abstract
Cryptogenic multifocal ulcerous stenosing enteritis is a rare idiopathic condition, characterized by multiple small intestinal fibrous strictures with superficial ulcerations. It typically has a chronic or relapsing clinical course and has been mainly reported from Asia and Europe. We report a case of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) in a patient with chronic anemia with melena and intermittent abdominal pain. The clinicopathological features of CMUSE are different from other small bowel disease. Our patient had a remarkable response to adalimumab. The area of gene mutations in CMUSE is promising but need further investigation.
Highlights
Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare idiopathic disease characterized by multiple small intestinal fibrous strictures with superficial ulcerations with a chronic or relapsing clinical course responding favorably to glucocorticosteroids
We report a patient with chronic anemia with melena and intermittent abdominal pain who was diagnosed with CMUSE by small bowel resection
All of them presented with anemia and 10/15 patients underwent multiple small bowel resections due to recurrent strictures
Summary
Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare idiopathic disease characterized by multiple small intestinal fibrous strictures with superficial ulcerations with a chronic or relapsing clinical course responding favorably to glucocorticosteroids. It has been mainly reported from Asia and Europe. We report a patient with chronic anemia with melena and intermittent abdominal pain who was diagnosed with CMUSE by small bowel resection
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