Datia Langhans cells as tuberculous lymphadenitis diagnose parameter based on chemical reaction

Abstract

The incidence of tuberculosis in Indonesia increases every year, resulted in increased cases of tuberculous lymphadenitis. The histopathological picture is often similar to other types of lymphadenitis. This study was an in-depth exploration of the anatomical pathology of Langhans datia cells and necrosis in tuberculous lymphadenitis. This research used secondary data from medical record of the lymph node paraffin blocks in the Anatomical Pathology Department of Sadikin Hasan General Hospital Bandung from January to December 2017. There are 322 medical records of tuberculosis lymphadenitis patients, consisting of 179 types of tuberculous lymphadenitis, 144 types of non-lymphadenitis specific, and nine types of granulomatous lymphadenitis. In all kinds of lymphadenitis, necrosis shows a general picture, whereas datia Langhans are more dominant in the tuberculous and granulomatous lymphadenitis type. The description of necrosing in lymphadenitis is tuberculous type 176(98.3%), non-specific type 120(83.3%), and granulomatous type 7(77.8%), while datia Langhans cells are more common in 132(73.7%) tuberculosis lymphadenitis, and granulomatous lymphadenitis 7(77.8%), compared with non-specific lymphadenitis 42(29.2%). This study concludes that there is necrosis in almost every type of lymphadenitis, whereas datia Langhans cells are lower in the tuberculous and granulomatous lymphadenitis.