Abstract
Sequence-defined and information coding macromolecules suitable for data storage materials were synthesized via a combination of two multicomponent reactions. Thus, a well-established protocol based on the Passerini reaction was combined for the first time with the Biginelli reaction for monomer synthesis to explore new sequence-defined materials by exploiting the high structural variety of two multicomponent reactions. The information was encoded via the variation of six different components per repeating unit choosing from a list of more than 100 components that can potentially be applied. The structural variety of the oligomers that can achieved using this approach offers an information density of up to 24 bits per repeat unit. The information was read out via tandem mass spectrometry, wherein the predominant fragmentation processes were identified and subsequently applied for reading out the information contained within several macromolecules, i.e. by sequencing and re-establishing the structure of these macromolecules.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
