Abstract
It is of interest to discuss the feasibility for data mining technology enabled antiretroviral therapy (ART) for HIV positive patients at the University of Gondar Specialized Teaching Hospital, Ethiopia. The Knowledge Discovery in Databases (KDD), which is in an iterative process where evaluation measures enhanced, is used to prepare the data set for ART in HIV positive patients. A decision tree J48 model that is the implementation of algorithm ID3 (Iterative Dichotomiser 3) developed by the WEKA project team is used in this study. The J48 model was built with pruned and without pruned parameters by selecting two different test modes for 10-fold cross validation with percentage split. Results using J48 pruned decision tree with 10-fold cross validation produces 80.5% prediction precision for ART starter prognosis enabled treatment in clinical settings.
Highlights
Ethiopia is among the countries most heavily affected by widespread HIV infection
Gondar University Hospital in Ethiopia is a tertiary referral teaching hospital with 350 beds giving service to more than 5 million people living in the vicinity areas
The hospital scaled up its HIV/AIDS related care with the introduction of free antiretroviral therapy (ART) service in 2005
Summary
Ethiopia is among the countries most heavily affected by widespread HIV infection. The first evidence of HIV epidemic in Ethiopia was detected in 1984 [1]. Gondar University Hospital in Ethiopia is a tertiary referral teaching hospital with 350 beds giving service to more than 5 million people living in the vicinity areas. The hospital started to provide HIV/AIDS related services in 2003 with limited scope for shortage of trained manpower and fee based Antiretroviral (ARV) drugs. The hospital scaled up its HIV/AIDS related care with the introduction of free ART service in 2005. The hospital is fully staffed with trained HIV/AIDS health care providers and is supported by a PEPFAR funded international Non-Governmental Organization (NGO), International Training and Education Center for Health (I-TECH), in the area of capacity building with technical and financial support. According to Gondar University Hospital June 2010 hospital HIV/AIDS report, there has been a total of 8377 patients enrolled to the HIV care program, out of which 5566 patients started ART. There are a cumulative 855 patients who were dropped out and 152 lost from follow-up patients making the overall active patients on ART to 3370 [2]
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