Abstract
The aim of this study is to explore the clinical effects of Chinese medicine in the treatment of stable angina pectoris in coronary heart disease. Chinese medicine has multitarget, multilevel, and multilink effects in the treatment of coronary angina, which can significantly improve patients' symptoms. Its mechanism of action involves multiple levels such as regulating lipid metabolism, improving platelet function, antioxidant, and protecting endothelial function. The design was based on data mining to analyse the dosing pattern of modern Chinese medicine for the treatment of stable angina pectoris in coronary heart disease. The number of episodes of angina pectoris, the duration of the episodes, and the changes in the electrocardiogram before and after taking the medicine were observed and compared between the two groups. The number and duration of angina attacks ((2.23 ± 0.77) per week and (1.31 ± 0.34) min/time, respectively) in the study group were found to be significantly better than those in the control group ((3.86 ± 1.03) per week and (2.46 ± 1.21) min/time, respectively).
Highlights
Coronary atherosclerotic heart disease due to functional changes in the coronary arteries, is collectively known as coronary heart disease [1]
Angina pectoris is a clinical syndrome characterised by chest pain due to temporary myocardial ischaemia and is the most common manifestation of coronary heart disease. e onset of coronary angina is closely related to endothelial dysfunction [2], platelet activation, inflammatory response, plaque rupture, thrombosis, and abnormal serum lipid metabolism. is disease belongs to the category of “chest paralysis and heart pain” in Chinese medicine, and the pathogenesis is “original deficiency and symptomatic deficiency.”
Chinese medicine treatment of angina pectoris in coronary artery disease follows the principle of evidence-based treatment and adopts treatment methods such as benefiting Qi, nourishing Yin, invigorating Blood, resolving blood stasis, resolving phlegm, and warming Yang, which has shown certain efficacy advantages [3]
Summary
Coronary atherosclerotic heart disease due to functional changes (stenosis) in the coronary arteries, is collectively known as coronary heart disease [1]. Astragalus membranaceus is effective in nourishing Qi and fixing the surface of the body, diuretic, and musclebuilding and can be used for hypertension, diabetes, and chronic rhinitis; Radix Codonopsis pilosula is effective in nourishing the middle of the body, strengthening the immune system, enhancing the blood-forming function of the organs, and dilating blood vessels and is effective for spleen deficiency and palpitations; Panax ginseng is effective in dispersing blood stasis and stopping bleeding and can be used to treat vomiting of blood, blood in the stool, and stabbing pain in the chest and abdomen; Salvia metrorrhagia is effective in promoting pain and activating blood circulation to remove blood stasis It can remove chest paralysis and relieve heat and pain. Chinese Medicine in the Treatment of Coronary Heart Disease e action of TCM in treating diseases is achieved through a multisite, multitarget, and multilevel mechanism of holistic regulation, which in turn is achieved through different combinations of TCM
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