Abstract

Analysis of variance of daily quality control sera in all 12 channels of a sequential multiple analyser have shown far greater variability from day to day than variability within a given day. Concurrently, a similar analysis of results of truncated patients' tests have revealed similar highly significant daily fluctuations in some channels. Daily fluctuations in the mean of these tests have shown a high degree of correlation with daily variation in the mean value of 2 different quality control sera suggesting that in certain tests the daily mean may be a valuable adjunct to conventional quality control procedures. A lack of linearity which occurred in one of the channels duriag the investigation gave a practical example of the fluctuations in the pooled sera used and their relatienship to truncated patients’ tests. The data also suggested criteria which may be of assistance in the selection of truncation points and tests likely to show relationship between serum pool and truncated patients’ tests.

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