Abstract
Aim: To review the effects of diabetes-related diseases on the healing process and amputation decision in diabetic foot ulcers (DFU), negative pressure wound therapy (NPWT) results, and current treatment approaches.
 Materials and Methods: The study was planned as retrospective and cross-sectional. Data of patients who were admitted to our clinic due to DFU and were treated were examined. A total of 38 patients were included in the study. The results of patients (n=19) who underwent periodic debridement and classic dressing were compared with the results of patients (n=19) who underwent NPWT. Healing in patients was achieved by amputation (n=8), repair with partial thickness grafts or flaps (n=10), and secondary epithelialization development (n=10). The effect of diabetes-related peripheral arterial disease (PAD), cardiovascular disease (CVD), chronic kidney disease (CKD), diabetic retinopathy (DRP), and previous amputation history (AH) on recovery time was examined. The predictive importance of diabetes-related diseases for amputation was investigated.
 Results: It was determined that diabetes-related diseases caused a delay in wound healing. [PAD (p
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