Abstract
Cystic hygroma is a type of lymphangioma and is located most frequently in the head and neck region, followed by axilla, superior mediastinum, and mesentery and retroperitoneal. Its occurrence in upper extremity is rarely reported in literature. We report a newborn baby with Down's syndrome presented with cystic hygroma in his left arm and forearm. Patient was treated with OK-432 for the swelling of the left arm. However, patient presented at five months of age with severe sepsis secondary to gangrene of left arm and concomitant meningitis which subsequently led to his death. Picibanil aka OK-432 has been increasingly used for the last two decades for the treatment of cystic hygroma with much success. However, few literatures report of serious morbidity with its use. More case controlled studies should be carried out to further understand the side effects of sclerosant therapy, as it has the potential to be ideal treatment for cystic hygroma in the future.
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