Abstract
Ovarian cancer is the leading cause of death due to gynecologic malignancies, and approximately 90% of ovarian cancers derive from the ovarian surface epithelium (OSE). Prostaglandins (PG) and their synthesizing cyclooxygenase enzymes (specifically COX-2) have been implicated in ovarian carcinogenesis. The present study investigates the expression of COX-1, COX-2, and other prostaglandin synthesis enzymes in normal monkey OSE.
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