Abstract
In a series of articles published in La Pediatria, Di Cristina, Sindoni, and Caronia1 describe a small diplococcus which they are able to obtain in culture from scarlet fever. These authors attribute certain specific reactions to this diplococcus which resemble the reactions obtained with the hemolytic streptococcus isolated from cases of scarlet fever in this country. The diplococcus has been obtained in blood cultures from scarlet fever and grown in media containing fragments of guinea pig tissue. When the filtrates of these cultures are injected intracutaneously, the response is apparently identical with that resulting from an intracutaneous inoculation with a filtrate of Streptococcus scarlatinae. These authors have prepared vaccines which they believe are capable of inducing an active immunity in persons susceptible to scarlatina.In 1925 Brokman2 and his associates undertook a comparison of the properties of scarlatinal hemolytic streptococcus and this diplococcus of Di Cristina and Caronia. Carboliz...
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