Abstract
Cutaneous papillomas developed on the left front foot and leg of a 1-year-old opossum born and raised in captivity. They later occurred on the left ear flap. The papillomas began to regress 6 months after their first appearance and had almost disappeared by 1 year. The papillomatous projections had a hyperplastic stratified squamous epithelium and a connective tissue base and core. Virus particles similar to those of the papova group were found by electron microscopy in negative-stained suspensiens. They were approximately 50 mµ in diameter. Virus-containing suspensions from the opossum wart and human papillomas did not produce pqpillomas in other opossoms when inoculated intradermally or rubbed into scarified skin. The possibility that the opossum papillomas originated from exposure to papillomas on the hand of an animal caretaker could not be determined.
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