Abstract
Cutaneous and systemic plasmacytosis is an exceedingly rare entity arising primarily in patients of Japanese descent. Only 5 non-Japanese cases have been reported in the literature.1-6 This condition is characterized by a cutaneous polyclonal plasma cell infiltrate accompanied by polyclonal hypergammaglobulinemia. Extracutaneous involvement with infiltration of lymph nodes, lungs, liver, spleen, and kidney can occur. We describe a Chinese patient who presented with diffuse reddish-brown macules, hypergammaglobulinemia, and reactive lymphadenopathy, which are hallmarks of this condition.
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