Abstract
Background: Primary hyperparathyroidism (PHPT) is a common clinical endocrine disorder. It is the most common cause of hypercalcemia in the outpatient setting. This review presents a brief summary of the new trends of presentation, diagnosis and management PHPT. Data Sources: PubMed (National Library of Medicine) articles, and Memorial Library archives of the University of Wisconsin System. Conclusions: PHPT occurs at any age, but it is most commonly seen in people over the age of 50 years and postmenopausal women. The current presentation of PHPT shifts from the classical symptomatic form to the asymptomatic form; however, parathyroidectomy is still the treatment of choice for both symptomatic and asymptomatic forms. In the past, bilateral neck exploration and intraoperative identification of all 4 parathyroid glands was the standard of treatment, nevertheless, nowadays, with the introduction of the preoperative and intraoperative localization techniques, the minimally invasive parathyroidectomy has evolved
Highlights
PHPT occurs at any age, but it is most commonly seen in people over the age of 50 years and postmenopausal women
Bilateral neck exploration and intraoperative identification of all 4 parathyroid glands was the standard of treatment, nowadays, with the introduction of the preoperative and intraoperative localization techniques, the minimally invasive parathyroidectomy has evolved
Primary hyperparathyroidism (PHPT) is defined by an abnormal increase in the intrinsic activity of the parathyroid gland(s) that result in elevated parathyroid hormone (PTH) levels [1,2]
Summary
PHPT occurs at any age, but it is most commonly seen in people over the age of 50 years and postmenopausal women. The current presentation of PHPT shifts from the classical symptomatic form to the asymptomatic form; parathyroidectomy is still the treatment of choice for both symptomatic and asymptomatic forms. Bilateral neck exploration and intraoperative identification of all 4 parathyroid glands was the standard of treatment, nowadays, with the introduction of the preoperative and intraoperative localization techniques, the minimally invasive parathyroidectomy has evolved
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