細菌代謝に対するオキシンCu, Co錯塩の影響

Abstract

Using the standard strains of Sh. flexneri and Staphy. aureus taken from the departmental stock, the author studied the effects of oxine, Cu++, Co++, combination of oxine-Cu++ and that of oxine-Co++ on the growth of bacteria and the glucose metabolism during their growth. The following results were obtained.1) The cooperative inhibition of oxine and Cu++ or oxine and Co++ on the growth was revealed most strikingly when oxine and metal ions came near equal concentrations. Of course, it was necessary to be kept both oxine and metal ions are exceeded a certain concentrations for revealing their inhibitory effects.2) The accumulation of pyruvate and lactate in the media was markedly increased in oxine or Co++ added media, on the other hand the accumulation of the metabolites from glucose was decreased in the case of Cu++ added media compaired with control.3) It was found that the metabolite acumulated slightly much in the media added oxine and Cu++ or oxine and Co++ than control media.