Crystal structure, spectroscopic and magnetic properties, and antimicrobial activities of cobalt(II) 2-methylthionicotinate complexes with N-heterocyclic ligands

Abstract

Synthesis and characterization of 10 new 2-methylthionicotinate (2-MeSnic) Co(II) complexes, namely, [Co(2-MeSnic)2L2(H2O)2] · nH2O (L is N,N-diethylnicotinamide—Et2nia, ethylnicotinate—Etnic, nicotinamide—nia, isonicotinamide—isonia, N-methylnicotinamide—N-Menia, furo[3,2-c]pyridine—fpy, 2,3-dimethylfuro[3,2-c]pyridine—Me2fpy or benzo[4,5]furo[3,2-c]pyridine—Bfp; n is 0, 1 or 2) as well as [Co(2-MeSnic)2L2] (L is ronicol—ron or 2-methylfuro[3,2-c]pyridine—Mefpy), are reported. The characterizations were based on physico-chemical and spectroscopic methods. The crystal structure of one of the complexes has been determined. In the molecular complex [Co(2-MeSnic)2(Me2fpy)2(H2O)2], the Co(II) central atom, located at a symmetry centre, is octahedrally coordinated by an oxygen atom of the unidentate 2-MeSnic carboxyl group, the nitrogen atom of the pyridine ring of Me2fpy, a water molecule and the corresponding centrosymmetrically located atoms. Also, biological activity of the complexes against various strains of bacteria and filamentous fungi has been investigated. It is concluded that by complexation of these nicotinate derivatives their biological activities are elevated.