Abstract
Specific binding of chemotactic peptides to receptors in rabbit neutrophils was enhanced in the presence of aliphatic alcohols — especially n-propanol and n-butanol. The effect was concentration dependent with maximum increases in specific binding of 2.6 and 3.0 fold in the presence of 2.5% n-propanol and n-butanol respectively. The results indicate that up to 65% of the receptors are cryptic and unavailable for ligand interactions. It is suggested that minute to minute modulation of chemotactic responsiveness could occur by controlling at the membrane level the number of receptors exposed to chemotactic stimuli.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Biochemical and Biophysical Research Communications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
