Abstract
In this paper, we consider a binary response model for the analysis of the two-treatment, two-period and four-sequence crossover design. We have introduced intra-patient drug dependency parameter in the model and provide two tests for the hypothesis of equality of treatment effects. We employ Monte Carlo simulation to compare our tests and a test that works under parallel design on the basis of type I error rate and power. We find that our procedures are dominant over the competitor with respect to power. Finally, we use a data set to illustrate the applicability of our procedure.
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