Critical Mass: Use of Pediatric Massive Transfusion Protocol after Catastrophic Cerebral Aneurysm Rupture

Abstract

Introduction: Although less common than its adult counterpart, pediatric massive transfusion remains an active area of research to reduce patient harms. Massive transfusion is generally defined as the transfusion of the equivalent of one total blood volume (TBV) calculated as mL/kg based on the patient’s age group (e.g. 80mL/kg for infants) within 24 hours or half of total blood volume within 12 hours. Balanced transfusion, such as with a 1:1:1 (pRBC:platelet:plasma) transfusion ratio, is associated with improved survival in adult but not pediatric literature. Case Report: We present the case of a 9-month-old previously healthy …