Abstract
Ca++/cAMP response element binding protein (CREB), phosphoCREB, and c-Fos-like (c-FL) immunoreactivity (IR) were examined in the nucleus of the solitary tract (NTS) and parabrachial nucleus (PBN) after peripheral cholecystokinin (CCK). c-FLIR was observed only after CCK, but CCK did not alter high basal levels of CREB-IR and phosphoCREB-IR. PhosphoCREB may be necessary but is not sufficient to induce c-Fos after CCK injection.
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