Creation and evaluation of a two-/three-dimensional molecular database for drugs used to target the respiratory system

Abstract

IntroductionPharmacy undergraduate education has seen many changes throughout the years in order to provide a holistic approach to meet the needs of the current pharmacy profession. Nowadays educators are recognizing that molecular databases serve as a valuable reference point for clinical, physicochemical, and structural information. AimsThe aim of this study was to compile an electronic molecular database of drugs used in respiratory conditions and to assess its utility by carrying out a randomized control study on a pharmacy student cohort of 125 students. MethodTo carry out this study, structures and representations of drugs acting on the respiratory system were created, compiled in a database, and uploaded onto the university’s web site. An intervention lecture focusing on the molecular database was carried out with the experimental group, and students’ individual performance at different stages in the study was assessed and statistical results were then generated. ResultsA drug repository of 51 entries was created. It was concluded that a significant improvement in the marks was attained in the experimental group (n = 5.525 points) with respect to the control group. A general trend can be noticed whereby student performance increased following the intervention and then diminished with time, as evidenced by the scores attained later in the study. ConclusionsThis study provides evidence that student understanding and knowledge is enhanced when teaching practices take on an innovative approach. The cohort gave high ranking scores when asked about the various aspects of the database, thus shedding light on the need of its implementation within the course as a lecturing and studying aid.