Abstract
Computed tomography (CT) scans of 21 patients with eating disorders were compared with those of 14 nonpsychotic controls. Of 14 patients with anorexia nervosa, 8 had cerebral ventricular enlargement, and 4 of these also had cortical sulcal atrophy, both by global assessment as compared with none of the controls. Ventricular brain ratio (VBR) and third ventricular measurements were also significantly increased in anorectics in comparison with 5 bulimic patients or controls. CT abnormalities were significantly correlated with rate of and degree of weight loss from premorbid weight but not with loss from estimated minimal healthy weight. Of any clinical features of anorexia, only hypothermia correlated with CT scan abnormality. Review of other reports of CT abnormalities in anorectics and implications for further investigation are discussed.
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